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Gene Expression Literature Summary
Assay
Age
Immunohistochemistry (section)
10.5 DPC

15 matching records from 15 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cdkn1c  cyclin dependent kinase inhibitor 1C   (Synonyms: CDKI, Kip2, p57Kip2)
Results  Reference
1J:225434 Cesario JM, Landin Malt A, Deacon LJ, Sandberg M, Vogt D, Tang Z, Zhao Y, Brown S, Rubenstein JL, Jeong J, Lhx6 and Lhx8 promote palate development through negative regulation of a cell cycle inhibitor gene, p57Kip2. Hum Mol Genet. 2015 Sep 1;24(17):5024-39
1J:109529 El Wakil A, Francius C, Wolff A, Pleau-Varet J, Nardelli J, The GATA2 transcription factor negatively regulates the proliferation of neuronal progenitors. Development. 2006 Jun;133(11):2155-65
1J:139945 El-Bizri N, Guignabert C, Wang L, Cheng A, Stankunas K, Chang CP, Mishina Y, Rabinovitch M, SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis. Development. 2008 Sep;135(17):2981-91
1*J:119274 Georgia S, Soliz R, Li M, Zhang P, Bhushan A, p57 and Hes1 coordinate cell cycle exit with self-renewal of pancreatic progenitors. Dev Biol. 2006 Oct 1;298(1):22-31
1J:117093 Gui H, Li S, Matise MP, A cell-autonomous requirement for Cip/Kip cyclin-kinase inhibitors in regulating neuronal cell cycle exit but not differentiation in the developing spinal cord. Dev Biol. 2007 Jan 1;301(1):14-26
1J:162637 Hang CT, Yang J, Han P, Cheng HL, Shang C, Ashley E, Zhou B, Chang CP, Chromatin regulation by Brg1 underlies heart muscle development and disease. Nature. 2010 Jul 1;466(7302):62-7
1J:239830 Hirai M, Arita Y, McGlade CJ, Lee KF, Chen J, Evans SM, Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation. J Clin Invest. 2017 Feb 01;127(2):569-582
1*J:144758 Ho HY, Chang KH, Nichols J, Li M, Homeodomain protein Pitx3 maintains the mitotic activity of lens epithelial cells. Mech Dev. 2009 Jan-Feb;126(1-2):18-29
1*J:292838 Iulianella A, Stanton-Turcotte D, The Hedgehog receptor Patched1 regulates proliferation, neurogenesis, and axon guidance in the embryonic spinal cord. Mech Dev. 2019 Dec;160:103577
1J:130161 Misra K, Gui H, Matise MP, Prox1 regulates a transitory state for interneuron neurogenesis in the spinal cord. Dev Dyn. 2008 Feb;237(2):393-402
1J:157341 Monahan P, Rybak S, Raetzman LT, The notch target gene HES1 regulates cell cycle inhibitor expression in the developing pituitary. Endocrinology. 2009 Sep;150(9):4386-94
1*J:74094 Nagahama H, Hatakeyama S, Nakayama K, Nagata M, Tomita K, Nakayama K, Spatial and temporal expression patterns of the cyclin-dependent kinase (CDK) inhibitors p27Kip1 and p57Kip2 during mouse development. Anat Embryol (Berl). 2001 Feb;203(2):77-87
1J:276877 Qu X, Harmelink C, Baldwin HS, Tie2 regulates endocardial sprouting and myocardial trabeculation. JCI Insight. 2019 May 21;5
1*J:72601 Westbury J, Watkins M, Ferguson-Smith AC, Smith J, Dynamic temporal and spatial regulation of the cdk inhibitor p57(kip2) during embryo morphogenesis. Mech Dev. 2001 Nov;109(1):83-9
1J:40142 Yan Y, Frisen J, Lee MH, Massague J, Barbacid M, Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development. Genes Dev. 1997 Apr 15;11(8):973-83

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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory